Three years after giving birth to their daughter Harlow, Patricia Arquette has married her long-time boyfriend, actor Thomas Jane.

Arquette is the star of the popular mystery series "Medium." The actress plays Allison Dubois, a wife and mother with an ability to communicate with the dead and dream about the future.

It is the second marriage for both - Arquette (38) previously wed actor Nicolas Cage while Jane (37) was married to Aysha Hauer, the daughter of actor Rutger Hauer. The private ceremony was held at the Palazzo Contarini in Venice, Italy with only of close family members on hand for the event.

Jane has had roles in the original "Buffy The Vampire Slayer" movie, Steven King's "Dreamcatcher" and "Boogie Nights," the porn industry story that made it to mainstream media.